How Pulmozyme works to fight cystic fibrosis (CF)
It works to fight CF, even when you can’t feel it
In clinical studies, Pulmozyme made mucus thinner and looser, which can make it easier to clear your lungs. CF often requires several different medicines as part of a treatment routine. Not all medicines work the same, so your doctor will prescribe multiple therapies to help you fight CF.
How Pulmozyme works to fight cystic fibrosis
Laboratory studies show that Pulmozyme cuts apart extracellular DNA by acting like an enzyme* naturally found in the lungs. By cutting this extracellular DNA, Pulmozyme helps make the thick, sticky mucus that your lungs produce thinner and looser.
*Enzymes are proteins created by the body to help speed up chemical reactions (such as the breakdown of molecules).
Why is Pulmozyme important?
In cystic fibrosis, your lungs produce extra-thick, sticky mucus. In laboratory studies, Pulmozyme made this mucus thinner and looser.
CF mucus before Pulmozyme
CF mucus after Pulmozyme
A study of cystic fibrosis patients 5 years of age and older with a forced vital capacity (FVC) of greater than or equal to 40% of predicted found:
Patients taking Pulmozyme daily had a lower risk of developing lung infections requiring intravenous (IV) antibiotics and showed an improvement in lung function, compared with those not taking Pulmozyme.
Starting treatment with Pulmozyme
Before taking your Pulmozyme, it is important to receive training from your CF Care Team. Here's what you will need to get started:
- Your Pulmozyme dose
- Nebulizer
- Compressor
Discussing Pulmozyme with your doctor
Use this Discussion Guide to help prepare for your doctor’s appointment and get the answers you’ll need for your everyday Pulmozyme treatment.
Need help paying for Pulmozyme?
Get info on our financial support programs
Getting started on Pulmozyme?
Learn about what you need to do to prepare for treatment